About Us
ABOUT US
Company Profile
Founded in April 2019, RNACure BioPharma is an innovative drug company focused on mRNA technology innovation and product development. We have built a full-chain mRNA drug technology platform spanning target discovery, sequence design, delivery systems, manufacturing processes, quality control, supply chain, and industrialization. The core team comprises leading scientists from Harvard, Yale, the Karolinska Institute, Peking University, PUMC, and other renowned institutions, with more than a decade of mRNA research experience. We are committed to breakthroughs in foundational mRNA technologies, building an integrated R&D-to-manufacturing platform, advancing an end-to-end mRNA industry ecosystem, accelerating clinical translation of mRNA medical products, and driving development across infectious disease vaccines, cancer vaccines, protein replacement therapy, gene-editing therapy, and veterinary vaccines, aiming to become a global leader in mRNA drug R&D.
Meaning of RNACure
In Chinese mythology, the blue magpie is a sacred bird. Legend says the Queen Mother of the West had three blue birds: one was sent as a messenger to the Han emperor, and two accompanied her in service. She is a deity of auspiciousness and longevity. As a messenger, the blue magpie's long tail symbolizes health and longevity. RNACure seeks to unlock more functions of mRNA to enable easier, safer, and more economical mRNA therapies. We have built a simple, one-step mRNA drug development platform spanning mRNA synthesis, early target discovery, and rapid product line expansion, focusing on mRNA vaccines and mRNA-based therapies for severe diseases.
Development History
DEVELOPMENT HISTORY

2017

mRNA program officially launched

2018

Key breakthroughs in mRNA synthesis; batch synthesis of Cap1 cap analogs; established in-house raw material supply chain for mRNA synthesis

2019

RNACure BioPharma officially founded

Scaled mRNA production (100 mg)

2020

Wangu R&D Center established

Fully advanced mRNA vaccine R&D

2021

Jan: Signed strategic agreement with a leading veterinary vaccine company

Apr: Signed strategic agreement with Walvax; opened 2,000 sqm R&D center

May: First batch of variant COVID-19 mRNA vaccine (RQ3013) produced

Aug: Partnered with Fudan University to establish China's first 'mRNA International Innovation Center'

Nov: RQ3013 included as a key project under the State Council's Joint Prevention and Control mechanism vaccine R&D task force

2022

Jan: Tripartite agreement with Fudan University and Walvax to co-develop an mRNA COVID-19 vaccine

Aug: RQ3013 received NMPA clinical trial approval

Dec: Phase III efficacy trial for RQ3013 launched in China

2023

Jun: Phase III efficacy trial for variant COVID-19 mRNA vaccine succeeded

Aug: RQ3013 initiated conditional approval application in China

Nov: RQ3033 received national emergency use authorization

RNACure's Wangu R&D Center is located in Wangu Science Park, Shanghai, with about 3,000 square meters of laboratory space. The center brings together core researchers from Fudan University, Shanghai Jiao Tong University, and institutions such as the Chinese Academy of Sciences, Peking University, and PUMC, covering clinical medicine, biochemistry, biophysics, protein structure, organic chemistry, medicinal chemistry, public health, and more. The center focuses on mRNA drug innovation and advances applications across infectious disease vaccines, cancer vaccines, rare disease vaccines, veterinary vaccines, and more. It will continue to attract top talent nationwide and globally to lead the field of mRNA innovation.
RNACure's Shaoxing pilot base is planned for the Binhai New Area Life & Health Science Park. Phase I covers about 3,000 square meters, building pilot production platforms for mRNA raw materials, mRNA formulations, and biological raw materials. The Shaoxing base is a key domestic industrial R&D site (in addition to Houston) and will support translation of laboratory results into industrialization, provide capacity for RNACure's innovation production, and foster mRNA industrial clustering. It aims to build an end-to-end demonstration chain from R&D to production, sales, and application along the mRNA supply chain.
In 2023, RNACure plans to build a 5,000-square-meter R&D center and a 10,000-square-meter GMP manufacturing base in Songnan Town and Luodian Town, forming a "south R&D, north manufacturing" layout. This will enable more than 10 preclinical and clinical projects in infectious disease vaccines, tumor immunotherapy, protein replacement therapy, and gene-editing therapies for rare diseases. The sites will support production of 50 million doses of clinical-trial mRNA drugs and deliver a digital, integrated mRNA drug development solution from concept to execution, improving quality, speed, scale, and cost, and unleashing the potential of the platform.
Honors
HONORS
Shanghai High-Tech Enterprise
Shanghai High-Tech Enterprise
Shanghai Specialized and Innovative Enterprise
Shanghai Specialized and Innovative Enterprise
Member Unit of China Vaccine Industry Association
Member Unit of China Vaccine Industry Association
Industrialization Base of Ministry of Education Engineering Research Center for Gene Technology
Industrialization Base of Ministry of Education Engineering Research Center for Gene Technology
Baoshan District Enterprise Technology Center
Baoshan District Enterprise Technology Center
Baoshan Postdoctoral Innovation Practice Base - RNACure Workstation
Baoshan Postdoctoral Innovation Practice Base - RNACure Workstation
2023 Future Healthcare Top 100
2023 Future Healthcare Top 100
Baoshan Innovative Vaccine Chain Leading Enterprise
Baoshan Innovative Vaccine Chain Leading Enterprise
Top 50 Most Innovative Biopharmaceutical Enterprises in China
Top 50 Most Innovative Biopharmaceutical Enterprises in China
C7 Building, Floors 7-9, Wangu Science Park, Yangpu District, Shanghai
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